The LOCI (Letrozole Or Clomifene for ovulation Induction) trial is a proposed new study to determine the best treatment for ovulation induction (OI). This is planned to be a 2×2 factorial design trial, so that women will first be randomised to receive clomifene or letrozole, then a second randomisation will
decide if they receive metformin or placebo.

The national trial team would be very grateful if you could complete the short survey below to obtain information about the number of patients seen at your hospital for OI and the treatment regime used: https://goo.gl/forms/xYOChhVrV5OFKFGU2